2-Methyl-4-phenyl-3,4-dihydro-quinazoline

Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 1;67(Pt 4):o923-4. doi: 10.1107/S1600536811009664. Epub 2011 Mar 19.

Abstract

The title compound, C(15)H(14)N(2), was formed during the lithia-tion of 2-methyl-quinazoline with phenyl-lithium followed by hydrolysis of the inter-mediate lithium 2-methyl-4-phenyl-4H-quinazolin-3-ide. NMR spectra as well as single-crystal X-ray structural data indicate that the reaction product to have the same structure in chloro-form solution as in the crystalline state. The phenyl substituent is twisted out of the plane of the 3,4-dihydro-quinazoline ring system by 86.47 (7)°. In the crystal, inter-molecular N-H⋯N inter-actions connect the mol-ecules into infinite chains.