Vaginal treatment of endometrial cancer: role in the elderly

World J Surg Oncol. 2011 Jul 13:9:74. doi: 10.1186/1477-7819-9-74.

Abstract

Background: To compare abdominal hysterectomy, the most currently used for treating cancer of the endometrium, to the vaginal hysterectomy in term of survival, morbidity and failure rates.

Methods: We retrospectively analyzed 68 cases divided into two sub-groups. A study group of 31 cases received vaginal surgery; a control group of 37 cases was treated with a laparotomy. Mean operative time, median hospital stay, intra- and post-operative complications, DFS and OS time as well as occurrence of local or distant recurrences have been evaluated and reported. Cases included patients with a higher rate of medical morbidities (p = 0.01) than controls.

Results: Mean age was 76.2 and 70.4 years in the vaginal (V) group and abdominal (A) group respectively. Mean operative time was longer for the group A. Group V patients had a lower mean post-operative hospital stay (p < 0.05). Differences in the two groups regarding intra- and post-operative complications, occurrence of local or distant recurrences and DFS time were not statistically significant. Disease specific survival time at 5 years scored 97% for group V, and 97% for group A.

Conclusions: Results show how vaginal approach had a similar outcome in selected patients. Vaginal surgery could therefore be the proper choice in patients with early stages and lower surgical risk, in addition to elderly patients exposed to a higher surgical risk.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Endometrial Neoplasms / diagnosis
  • Endometrial Neoplasms / mortality
  • Endometrial Neoplasms / surgery*
  • Female
  • Humans
  • Hysterectomy, Vaginal / methods*
  • Italy / epidemiology
  • Laparoscopy / methods
  • Length of Stay
  • Neoplasm Staging
  • Retrospective Studies
  • Sarcoma, Endometrial Stromal / diagnosis
  • Sarcoma, Endometrial Stromal / mortality
  • Sarcoma, Endometrial Stromal / surgery*
  • Survival Rate / trends
  • Treatment Outcome
  • Vagina