Invasive Streptococcus pneumoniae in children, Malawi, 2004-2006

Emerg Infect Dis. 2011 Jun;17(6):1107-9. doi: 10.3201/eid/1706.101404.

Abstract

Of 176 invasive Streptococcus pneumoniae isolates from children in Malawi, common serotypes were 1 (23%), 6A/B (18%), 14 (6%), and 23F (6%). Coverage with the 7-valent pneumococcal conjugate vaccine (PCV) was 39%; PCV10 and PCV13 increased coverage to 66% and 88%, respectively. We found chloramphenicol resistance in 27% of isolates and penicillin nonsusceptibility in 10% (by using meningitis breakpoints); all were ceftriaxone susceptible.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / pharmacology
  • Child
  • Child, Preschool
  • Drug Resistance, Bacterial
  • Female
  • HIV Infections / complications
  • Humans
  • Infant
  • Male
  • Microbial Sensitivity Tests
  • Pneumococcal Infections / diagnosis
  • Pneumococcal Infections / microbiology*
  • Pneumococcal Infections / mortality
  • Serotyping
  • Streptococcus pneumoniae / classification
  • Streptococcus pneumoniae / drug effects
  • Streptococcus pneumoniae / isolation & purification
  • Streptococcus pneumoniae / physiology*

Substances

  • Anti-Bacterial Agents