Abstract
The binding of seven multivalent glycoconjugates displaying linear or antenna-like structures and different electronic environments were evaluated towards PA-IL on a DNA-based carbohydrate microarray. The affinity can be modulated by the charge and the topology of the galactosylated derivatives.
This journal is © The Royal Society of Chemistry 2011
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Carbohydrates / chemistry*
-
Click Chemistry
-
DNA / chemistry
-
DNA / metabolism*
-
Glycoconjugates / chemistry
-
Glycoconjugates / metabolism*
-
Lectins / metabolism*
-
Microarray Analysis
-
Protein Binding
-
Pseudomonas aeruginosa / metabolism*
-
Spectrometry, Fluorescence
Substances
-
Carbohydrates
-
Glycoconjugates
-
Lectins
-
DNA