Treatment of cardiovascular implantable electronic device infection with daptomycin

Ahmad F Jebran; Aron F Popov; Dieter Zenker; Christian Bireta; Direndra Rajaruthnam; Martin Friedrich; Friedrich A Schoendube

doi:10.1111/j.1540-8159.2011.03163.x

Treatment of cardiovascular implantable electronic device infection with daptomycin

Pacing Clin Electrophysiol. 2012 Apr;35(4):e105-7. doi: 10.1111/j.1540-8159.2011.03163.x. Epub 2011 Jul 11.

Authors

Ahmad F Jebran¹, Aron F Popov, Dieter Zenker, Christian Bireta, Direndra Rajaruthnam, Martin Friedrich, Friedrich A Schoendube

Affiliation

¹ Department of Thoracic and Cardiovascular Surgery, University of Göttingen, Göttingen, Germany.

PMID: 21745225
DOI: 10.1111/j.1540-8159.2011.03163.x

Abstract

We describe a case of 83-year-old man who was admitted to our department for treatment of recurrent device-pocket infections. Our report shows that in a case of high-risk patient with a complicated cardiac implantable electric devices infection involving multidrug-resistent gram-positive pathogen, the application of daptomycin in combination with staged surgical therapy can be efficient and safe.

Publication types

Case Reports

MeSH terms

Aged, 80 and over
Anti-Bacterial Agents / therapeutic use*
Daptomycin / therapeutic use*
Defibrillators, Implantable / microbiology*
Device Removal / adverse effects
Drug Resistance, Multiple / drug effects
Humans
Male
Prosthesis-Related Infections / drug therapy*
Staphylococcal Infections / diagnosis
Staphylococcal Infections / drug therapy*
Staphylococcus haemolyticus / drug effects*
Treatment Outcome

Substances

Anti-Bacterial Agents
Daptomycin