Abstract
Two unnatural L-oligodeoxyribonucleotides, namely alpha- and beta-L-dT8pO(CH2)3OH, have been synthesized. These oligomers are resistant towards nuclease degradation. They do not show any UV detectable base pairing with beta-D-dA8 and poly rA.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Base Composition
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Cattle
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Indicators and Reagents
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Isomerism
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Magnetic Resonance Spectroscopy
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Oligodeoxyribonucleotides / chemical synthesis*
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Oligodeoxyribonucleotides / chemistry
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Oligodeoxyribonucleotides / metabolism
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Phosphoric Diester Hydrolases / metabolism
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Single-Strand Specific DNA and RNA Endonucleases / metabolism
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Spleen / enzymology
Substances
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Indicators and Reagents
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Oligodeoxyribonucleotides
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oligo (dT)
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Single-Strand Specific DNA and RNA Endonucleases
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Phosphoric Diester Hydrolases