Cytomegalovirus gB genotype distribution in Mexican children undergoing allogeneic bone marrow transplantation

Intervirology. 2012;55(4):318-20. doi: 10.1159/000328665. Epub 2011 Jul 5.

Abstract

We used nested multiplex polymerase chain reaction to determine the distribution of cytomegalovirus gB genotype in 30 Mexican children undergoing bone marrow transplantation. The genotypes were: gB1, 9/30 (30%); gB2, 8/30 (27%); gB3, 4/30 (13%), and gB4, 1/30 (3%); mixed genotypes were identified in 8/30 patients (27%). We conclude that the predominant genotypes identified were gB2 and gB1. The gB5 genotype was not detected, and a high proportion of mixed genotype was found.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Bone Marrow Transplantation / adverse effects*
  • Child
  • Child, Preschool
  • Coinfection / virology
  • Cytomegalovirus / classification*
  • Cytomegalovirus / genetics*
  • Cytomegalovirus / isolation & purification
  • Cytomegalovirus Infections / epidemiology
  • Cytomegalovirus Infections / virology*
  • Genotype
  • Humans
  • Infant
  • Mexico / epidemiology
  • Molecular Epidemiology
  • Multiplex Polymerase Chain Reaction
  • Polymerase Chain Reaction
  • Prevalence
  • Transplantation, Homologous / adverse effects*
  • Viral Envelope Proteins / genetics*

Substances

  • Viral Envelope Proteins
  • glycoprotein B, Simplexvirus