Vanadium inhalation in a mouse model for the understanding of air-suspended particle systemic repercussion

J Biomed Biotechnol. 2011:2011:951043. doi: 10.1155/2011/951043. Epub 2011 May 22.

Abstract

There is an increased concern about the health effects that air-suspended particles have on human health which have been dissected in animal models. Using CD-1 mouse, we explore the effects that vanadium inhalation produce in different tissues and organs. Our findings support the systemic effects of air pollution. In this paper, we describe our findings in different organs in our conditions and contrast our results with the literature.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Air Pollution / adverse effects*
  • Animals
  • Bone and Bones / drug effects
  • Bone and Bones / pathology
  • Central Nervous System / drug effects
  • Central Nervous System / pathology
  • DNA Breaks, Single-Stranded
  • Humans
  • Immune System / pathology
  • Inhalation
  • Liver / drug effects
  • Liver / pathology
  • Lung / drug effects
  • Lung / pathology
  • Lymph Nodes / drug effects
  • Lymph Nodes / pathology
  • Mice
  • Models, Animal
  • Particulate Matter / toxicity*
  • Reactive Oxygen Species / metabolism
  • Reproduction / drug effects
  • Spleen / drug effects
  • Spleen / pathology
  • Vanadium / toxicity*

Substances

  • Particulate Matter
  • Reactive Oxygen Species
  • Vanadium