Histological and functional changes in retrodiscal tissue following anterior articular disc displacement in the rabbit: review of the literature

Minerva Stomatol. 2011 Jul-Aug;60(7-8):349-58.
[Article in English, Italian]

Abstract

Aim: Numerous studies have shown how the disc displacement, which usually occurs in an antero-medial direction, can be a factor contributing to temporomandibular joint (TMJ) pain and dysfunction. The aim of this study was to ascertain, through a critical review of the literature, current knowledge relating to anterior articular disc (ADD) in the rabbit that constitutes an extremely suitable animal model for studying the human TMJ.

Methods: An electronic search of the MEDLINE database was performed without applying time or language restrictions and using the following key words: TMD, anterior disc displacement, rabbit, bilaminar zone. This was followed by a manual search. The articles identified were assessed to verify their pertinence, or otherwise, to the topic of investigation.

Results: The articles examined were divided into the following groups according to the topic (histological and/or functional) they dealt with: experimental animal models, joint changes, elastic fibers, collagen, chondrocytes and nervous tissue.

Conclusion: The papers reviewed covered many aspects, both microscopic and histochemical, of the dysfunctional picture o anterior ADD, furnishing a vast body of useful information, not only from the point of view of the results recorded, but also as regards the various surgical and analytical methods used.

Publication types

  • Review

MeSH terms

  • Animals
  • Collagen / analysis
  • Elastic Tissue / pathology
  • Fibrocartilage / pathology*
  • Fibrocartilage / surgery
  • Hernia / pathology*
  • Hernia / physiopathology
  • Humans
  • Ligaments, Articular / pathology
  • Ligaments, Articular / surgery
  • Models, Animal*
  • Pain / physiopathology
  • Rabbits / physiology*
  • Species Specificity
  • Temporomandibular Joint / innervation
  • Temporomandibular Joint Disorders / pathology*
  • Temporomandibular Joint Disorders / physiopathology
  • Temporomandibular Joint Disorders / surgery

Substances

  • Collagen