An enzymatic clinical chemistry laboratory experiment incorporating an introduction to mathematical method comparison techniques

Mark Duxbury

doi:10.1002/bmb.2004.494032040366

An enzymatic clinical chemistry laboratory experiment incorporating an introduction to mathematical method comparison techniques

Biochem Mol Biol Educ. 2004 Jul;32(4):246-9. doi: 10.1002/bmb.2004.494032040366.

Author

Mark Duxbury¹

Affiliation

¹ Department of Applied Science, Auckland University of Technology, Auckland, New Zealand. mark.duxbury@aut.ac.nz.

PMID: 21706732
DOI: 10.1002/bmb.2004.494032040366

Abstract

An enzymatic laboratory experiment based on the analysis of serum is described that is suitable for students of clinical chemistry. The experiment incorporates an introduction to mathematical method-comparison techniques in which three different clinical glucose analysis methods are compared using linear regression and Bland-Altman difference plots. The experiment may also be undertaken using simple glucose solutions by general biochemistry students.