ODORactor: a web server for deciphering olfactory coding

Bioinformatics. 2011 Aug 15;27(16):2302-3. doi: 10.1093/bioinformatics/btr385. Epub 2011 Jun 23.

Abstract

Summary: ODORactor is an open access web server aimed at providing a platform for identifying odorant receptors (ORs) for small molecules and for browsing existing OR-ligand pairs. It enables the prediction of ORs from the molecular structures of arbitrary chemicals by integrating two individual functionalities: odorant verification and OR recognition. The prediction of the ORs for several odorants was experimentally validated in the study. In addition, ODORactor features a comprehensive repertoire of olfactory information that has been manually curated from literature. Therefore, ODORactor may provide an effective way to decipher olfactory coding and could be a useful server tool for both basic olfaction research in academia and for odorant discovery in industry.

Availability: Freely available at http://mdl.shsmu.edu.cn/ODORactor

Contact: jian.zhang@sjtu.edu.cn

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Humans
  • Internet
  • Ligands
  • Mice
  • Odorants
  • Receptors, Odorant / chemistry*
  • Smell
  • Software*

Substances

  • Ligands
  • Receptors, Odorant