Rational design of a highly reactive ratiometric fluorescent probe for cyanide

Lin Yuan; Weiying Lin; Yueting Yang; Jizeng Song; Jiaoliang Wang

doi:10.1021/ol2013928

Rational design of a highly reactive ratiometric fluorescent probe for cyanide

Org Lett. 2011 Jul 15;13(14):3730-3. doi: 10.1021/ol2013928. Epub 2011 Jun 22.

Authors

Lin Yuan¹, Weiying Lin, Yueting Yang, Jizeng Song, Jiaoliang Wang

Affiliation

¹ State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, People's Republic of China.

PMID: 21696129
DOI: 10.1021/ol2013928

Abstract

A novel highly reactive ratiometric fluorescent cyanide probe was judiciously designed based on 2-formylacrylonitrile moiety as a new cyanide reaction site. A DFT study was conducted to rationalize the extremely high reactivity nature of the ratiometric fluorescent cyanide probe.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Fluorescent Dyes / chemistry*
Molecular Conformation
Molecular Structure
Nitriles / analysis
Nitriles / chemistry*
Spectrometry, Fluorescence

Substances

Fluorescent Dyes
Nitriles