Diastereoselectivity switch in cooperatively catalyzed three-component reactions of an aryldiazoacetate, an alcohol, and a β,γ-unsaturated α-keto ester

Jingjing Ji; Xia Zhang; Yingguang Zhu; Yu Qian; Jing Zhou; Liping Yang; Wenhao Hu

doi:10.1021/jo102423c

Diastereoselectivity switch in cooperatively catalyzed three-component reactions of an aryldiazoacetate, an alcohol, and a β,γ-unsaturated α-keto ester

J Org Chem. 2011 Jul 15;76(14):5821-4. doi: 10.1021/jo102423c. Epub 2011 Jun 13.

Authors

Jingjing Ji¹, Xia Zhang, Yingguang Zhu, Yu Qian, Jing Zhou, Liping Yang, Wenhao Hu

Affiliation

¹ Department of Chemistry, East China Normal University, Shanghai, People's Republic of China.

PMID: 21667947
DOI: 10.1021/jo102423c

Abstract

A highly switchable,diastereoselectivity-controlled, three-component reaction of aryldiazoacetate, alcohol,and β,γ-unsaturated α-keto esters has been achieved through a dual-metal cooperative catalysis strategy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetates / chemistry*
Alcohols / chemistry*
Catalysis
Crystallography, X-Ray
Esters / chemical synthesis
Esters / chemistry*
Ketones / chemistry*
Models, Molecular
Molecular Structure
Stereoisomerism

Substances

Acetates
Alcohols
Esters
Ketones