Thromboembolic events are uncommon after open treatment of proximal humerus fractures using aspirin and compression devices

Clin Orthop Relat Res. 2011 Dec;469(12):3332-6. doi: 10.1007/s11999-011-1942-7.

Abstract

Background: Thromboembolic phenomena have long been recognized as a major cause of morbidity and mortality in hospitalized patients, especially those undergoing reconstructive surgery. We have been empirically treating patients with aspirin, early ambulation, and mechanoprophylaxis after operative management of proximal humerus fractures. However, we have not established the incidence of postoperative deep vein thrombosis and pulmonary embolism in this population.

Questions/purposes: We determined the incidence of deep vein thrombosis and pulmonary embolism in patients having surgery for displaced proximal humerus fractures treated with our thromboprophylactic regimen.

Patients and methods: We prospectively followed 50 patients with proximal humerus fractures who underwent fixation with plate osteosynthesis (n = 40) or hemiarthroplasty (n = 10) between August 2005 and December 2008. Deep vein thrombosis prophylaxis consisted of oral enteric-coated aspirin, pneumatic calf compression pumps, and early ambulation in all patients unless medically contraindicated. Color-flow Doppler ultrasound of the affected arm and both lower extremities was performed at a mean of 14 days (range, 7-21 days) postoperatively to evaluate for deep vein thrombosis. All patients clinically suspected to have suffered a pulmonary embolism underwent a CT angiogram.

Results: We identified no patients with deep vein thrombosis or pulmonary embolism in this population.

Conclusions: Deep vein thrombosis and pulmonary embolism are not uncommon after major reconstructive surgery about the shoulder in untreated patients. Our data suggest these events can be low after surgery for proximal humerus fractures followed by a thromboprophylactic regimen including aspirin, mechanical devices, and early mobilization.

Level of evidence: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

MeSH terms

  • Aspirin / therapeutic use*
  • Comorbidity
  • Early Ambulation
  • Female
  • Fracture Fixation, Internal
  • Humans
  • Incidence
  • Male
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / prevention & control
  • Prospective Studies
  • Pulmonary Embolism / epidemiology*
  • Pulmonary Embolism / prevention & control
  • Shoulder Fractures / epidemiology
  • Shoulder Fractures / surgery*
  • Ultrasonography, Doppler, Color
  • Venous Thrombosis / epidemiology*
  • Venous Thrombosis / prevention & control

Substances

  • Platelet Aggregation Inhibitors
  • Aspirin