Low platelet reactivity is recovered by transfusion of stored platelets: a healthy volunteer in vivo study

J Thromb Haemost. 2011 Aug;9(8):1670-3. doi: 10.1111/j.1538-7836.2011.04392.x.
No abstract available

Publication types

  • Clinical Trial
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Diphosphate
  • Aryl Hydrocarbon Hydroxylases / genetics
  • Austria
  • Blood Platelets / drug effects*
  • Blood Platelets / metabolism
  • Blood Transfusion, Autologous
  • Cell Adhesion Molecules / blood
  • Clopidogrel
  • Cytochrome P-450 CYP2C19
  • Humans
  • Microfilament Proteins / blood
  • Phosphoproteins / blood
  • Phosphorylation
  • Pilot Projects
  • Platelet Aggregation / drug effects
  • Platelet Aggregation Inhibitors / administration & dosage*
  • Platelet Count
  • Platelet Function Tests
  • Platelet Transfusion*
  • Polymorphism, Single Nucleotide
  • Ticlopidine / administration & dosage
  • Ticlopidine / analogs & derivatives*

Substances

  • Cell Adhesion Molecules
  • Microfilament Proteins
  • Phosphoproteins
  • Platelet Aggregation Inhibitors
  • vasodilator-stimulated phosphoprotein
  • Adenosine Diphosphate
  • Clopidogrel
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Ticlopidine

Associated data

  • ClinicalTrials.gov/NCT01248351