Palladium-catalyzed three-component domino reaction for the preparation of benzo[b]thiophene and related compounds

Huanan Huang; Jing Li; Weining Zhao; Yanbo Mei; Zheng Duan

doi:10.1039/c1ob05571b

Palladium-catalyzed three-component domino reaction for the preparation of benzo[b]thiophene and related compounds

Org Biomol Chem. 2011 Jul 21;9(14):5036-8. doi: 10.1039/c1ob05571b. Epub 2011 Jun 6.

Authors

Huanan Huang¹, Jing Li, Weining Zhao, Yanbo Mei, Zheng Duan

Affiliation

¹ Chemistry Department, the Key Lab of Chemical Biology and Organic Chemistry of Henan Province, Zhengzhou University, Zhengzhou 450001, P. R. China.

PMID: 21647501
DOI: 10.1039/c1ob05571b

Abstract

A simple and efficient palladium-catalyzed three-component domino reaction of bromothiophenes with internal alkynes has been developed to produce benzo[b]thiophenes in moderate to good yields.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Molecular Structure
Organometallic Compounds / chemistry*
Palladium / chemistry*
Stereoisomerism
Thiophenes / chemical synthesis*
Thiophenes / chemistry

Substances

Organometallic Compounds
Thiophenes
benzothiophene
Palladium