Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

Xiaoqiang Chen; Xizhe Tian; Injae Shin; Juyoung Yoon

doi:10.1039/c1cs15037e

Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

Chem Soc Rev. 2011 Sep;40(9):4783-804. doi: 10.1039/c1cs15037e. Epub 2011 Jun 1.

Authors

Xiaoqiang Chen¹, Xizhe Tian, Injae Shin, Juyoung Yoon

Affiliation

¹ Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.

PMID: 21629957
DOI: 10.1039/c1cs15037e

Abstract

Oxidative and nitrosative stress induced by ROS/RNS play crucial roles in a wide range of physiological processes and are also implicated in various diseases, including cancer and neurodegenerative disorders. Sensitive and selective methods for the detection of ROS/RNS based on fluorescent and luminescent probes are of great use in monitoring the in vivo production of these species and elucidating their biological functions. This critical review highlights recent advances that have been made in the development of fluorescent and luminescent probes employed to monitor various ROS/RNS (132 references).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Fluorescent Dyes
Luminescence
Molecular Diagnostic Techniques
Molecular Probes*
Reactive Nitrogen Species / analysis*
Reactive Nitrogen Species / biosynthesis
Reactive Oxygen Species / analysis*
Reactive Oxygen Species / metabolism

Substances

Fluorescent Dyes
Molecular Probes
Reactive Nitrogen Species
Reactive Oxygen Species