Safety of liver transplantation with Chagas disease-seropositive donors for seronegative recipients

Liver Transpl. 2011 Nov;17(11):1304-8. doi: 10.1002/lt.22346.

Abstract

The shortage of organs for transplantation has prompted the investigation of extended criteria donors, such as donors with transmissible infectious diseases. Here we report our recent experience with liver transplantation using organs from donors who were serologically positive for Chagas disease. We also provide a review of the literature and emphasize donor screening and preventive measures.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Protozoan / blood
  • Brazil
  • Chagas Disease / immunology
  • Chagas Disease / transmission*
  • Female
  • Humans
  • Liver Diseases, Alcoholic / surgery*
  • Liver Transplantation / standards*
  • Male
  • Middle Aged
  • Tissue Donors*
  • Tissue and Organ Procurement / standards*
  • Trypanosoma cruzi / immunology*

Substances

  • Antibodies, Protozoan