A novel catalytic process for trifluoromethylation of bromoaromatic compounds

Chem Commun (Camb). 2011 Jul 7;47(25):7236-8. doi: 10.1039/c1cc12098k. Epub 2011 May 25.

Abstract

The palladium-catalyzed trifluoromethylation of aryl bromides has been achieved in micellar media. The micellar conditions result in enhanced yields and are applicable to bromoaromatics with ketone, aldehyde, hydroxyl and amine functionalities.

MeSH terms

  • Bromine / chemistry*
  • Catalysis
  • Fluorine / chemistry*
  • Green Chemistry Technology
  • Methylation
  • Micelles
  • Organic Chemicals / chemistry*

Substances

  • Micelles
  • Organic Chemicals
  • Fluorine
  • Bromine