The effect of aqueous extract of gross and commercial yerba mate (Ilex paraguariensis) on intra-abdominal and epididymal fat and glucose levels in male Wistar rats

Fitoterapia. 2011 Sep;82(6):818-26. doi: 10.1016/j.fitote.2011.04.011. Epub 2011 May 10.

Abstract

This study analyzed the plasma lipid profile, glucose levels and fat deposits in male rats treated with aqueous extract of gross yerba mate, commercial yerba mate or water. Yerba mate treatment did not change body weight gain and lipid profile. The consumption of gross yerba mate significantly increased blood glucose (6.6 mmol/L) as compared to the water (4.8 mmol/L) and commercial group (5.2 mmol/L) and decreased epididymal and intra-abdominal deposits (10.1mg/g and 23.7 mg/g of weight) as compared to the water (15.4 mg/g and 36.9 mg/g of weight) and commercial group (12.5mg/g and 28 mg/g of weight). The results suggest that gross yerba mate reduces fat more efficiently but produces a greater increase in blood glucose when compared to commercial yerba mate and water groups.

MeSH terms

  • Adipose Tissue / drug effects*
  • Adipose Tissue / metabolism
  • Animals
  • Blood Glucose / drug effects*
  • Blood Glucose / metabolism
  • Body Weight / drug effects
  • Epididymis / metabolism
  • Ilex paraguariensis / chemistry*
  • Intra-Abdominal Fat / drug effects
  • Male
  • Plant Components, Aerial / chemistry
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Polyphenols / chemistry
  • Polyphenols / isolation & purification
  • Polyphenols / pharmacology*
  • Random Allocation
  • Rats
  • Rats, Wistar
  • Saponins / chemistry
  • Saponins / isolation & purification
  • Saponins / pharmacology*
  • Xanthines / chemistry
  • Xanthines / isolation & purification
  • Xanthines / pharmacology*

Substances

  • Blood Glucose
  • Plant Extracts
  • Polyphenols
  • Saponins
  • Xanthines
  • methylxanthine