The Geneva brain collection

Ann N Y Acad Sci. 2011 May:1225 Suppl 1:E131-46. doi: 10.1111/j.1749-6632.2011.06008.x.

Abstract

The University of Geneva brain collection was founded at the beginning of the 20th century. Today, it consists of 10,154 formaldehyde- or buffered formaldehyde-fixed brains obtained from the autopsies of the Department of Psychiatry and, since 1971, from the Department of Geriatrics. More than 100,000 paraffin-embedded blocks and 200,000 histological slides have also been collected since 1901. From the time of its creation, this collection has served as an important resource for pathological studies and clinicopathological correlations, primarily in the field of dementing illnesses and brain aging research. These materials have permitted a number of original neuropathological observations, such as the classification of Pick's disease by Constantinidis, or the description of dyshoric angiopathy and laminar sclerosis by Morel. The large number of cases, including some very rare conditions, provides a unique resource and an opportunity for worldwide collaborations.

Publication types

  • Historical Article
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged, 80 and over
  • Aging / pathology
  • Anatomy, Cross-Sectional
  • Biological Specimen Banks* / history
  • Biological Specimen Banks* / organization & administration
  • Brain / anatomy & histology
  • Brain / cytology
  • Brain / pathology*
  • Child
  • Dementia / pathology
  • Female
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Male
  • Neurons / cytology
  • Neurons / pathology*
  • Switzerland
  • Universities