The asymmetric unit of the title compound, 2C(15)H(9)F(6)N(3)O·H(2)O, contains two independent Schiff base mol-ecules and one water mol-ecule. Both Schiff base mol-ecules exist in an E configuration with respect to the C=N double bonds and the dihedral angles between the benzene and the pyridine rings in the two mol-ecules are 17.53 (12) and 20.62 (12)°. In the crystal structure, mol-ecules are linked by inter-molecular N-H⋯O and C-H⋯O hydrogen bonds into infinite one-dimensional chains along the a axis. In addition, inter-molecular O-H⋯N, O-H⋯F, C-H⋯F and C-H⋯O hydrogen bonds further link these chains into a three-dimensional network. Weak π-π inter-actions with centroid-centroid distances in the range 3.6495 (17)-3.7092 (16) Å are also observed.