N-[3-Chloro-4-(3-fluoro-benz-yloxy)phen-yl]-6-iodo-quinazolin-4-amine

Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 26;66(Pt 7):o1810. doi: 10.1107/S1600536810021847.

Abstract

In the title mol-ecule, C(21)H(14)ClFIN(3)O, the bicyclic ring system has a twisted conformation; the two fused rings form a dihedral angle of 4.5 (1)°. The dihedral angles between the fused ring system and the benzene rings are 27.3 (6) and 5.3 (5)° while the dihedral angle between the benzene rings is 22.0 (5)°. In the crystal structure, weak inter-molecular N-H⋯N hydrogen bonds link the mol-ecules into chains propagating in [100]. A short inter-molecular distance of 3.806 (3) Å between the centroids of the fluorobenzene and iodobenzene rings suggests the existence of π-π stacking inter-actions.