Ethyl 5-(4-chloro-phen-yl)-2-[(Z)-(methoxy-carbon-yl)methyl-ene]-7-methyl-3-oxo-3,5-dihydro-2H-thia-zolo[3,2-a]pyrimi-dine-6-carboxyl-ate

Acta Crystallogr Sect E Struct Rep Online. 2009 Jan 23;65(Pt 2):o375. doi: 10.1107/S1600536809002451.

Abstract

The title compound, C(19)H(17)ClN(2)O(5)S, was synthesized by the reaction of ethyl 6-(4-chloro-phen-yl)-2-mercapto-4-methyl-1,6-dihydro-pyrimidine-5-carboxyl-ate and dimethyl acetyl-ene-dicarboxyl-ate in methanol. In the mol-ecule, the nearly planar thia-zole ring, with a mean deviation from the plane of 0.0108 (3) Å, is fused with a dihydro-pyrimidine ring in a flattened half-chair conformation.