(1R,3S,5R,6S)-6-Hydr-oxy-3-tosyl-oxy-tropan-8-ium chloride

Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 9;66(Pt 2):o317. doi: 10.1107/S1600536809055366.

Abstract

The title compound, C(15)H(22)NO(4)S(+)·Cl(-), is a hydrolysis product of lesatropane [(1R,3S,5R,6S)-6-acet-oxy-3-tosyl-oxytropane] hydro-chloride, a potential anti-glaucoma agent. As in lesatropane, the piperidine and pyrrolidine rings in the title compound adopt chair and envelope conformations, respectively. There are two mol-ecules in the unit cell with similar conformations. The crystal structure is stabilized by inter-molecular O-H⋯Cl and N-H⋯Cl hydrogen bonds.