[Study of Ingavirin antiviral activity against Mexican pandemic influenza virus A/H1N1/2009 in vitro and in vivo]

S Ya Loginova; S V Borisevich; V N Shchukina; M V Lykov; G V Borisevich; V P Bondarev; V E Nebolsin; O A Sutochnikova; A G Chychalin

[Study of Ingavirin antiviral activity against Mexican pandemic influenza virus A/H1N1/2009 in vitro and in vivo]

Antibiot Khimioter. 2010;55(11-12):17-21.

[Article in Russian]

Authors

S Ya Loginova, S V Borisevich, V N Shchukina, M V Lykov, G V Borisevich, V P Bondarev, V E Nebolsin, O A Sutochnikova, A G Chychalin

PMID: 21574420

Abstract

High in vitro and in vivo efficacy of Ingavirin against the Mexican pandemic influenza virus A/H1N1/2009, strains A/California/04/2009 (H1N1) and A/California/07/2009 (H1N1) vs. the reference drug Arbidol was studied and verified when used therapeutically and prophylactically.

MeSH terms

Amides / therapeutic use*
Antiviral Agents / therapeutic use*
Caproates
Dicarboxylic Acids / therapeutic use*
Humans
Imidazoles / therapeutic use*
Indoles / therapeutic use
Influenza A Virus, H1N1 Subtype / drug effects*
Influenza, Human* / drug therapy
Influenza, Human* / prevention & control

Substances

Amides
Antiviral Agents
Caproates
Dicarboxylic Acids
Imidazoles
Indoles
pentanedioic acid imidazolyl ethanamide
umifenovir