Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility

Fertil Steril. 2011 Jul;96(1):e9-e12. doi: 10.1016/j.fertnstert.2011.04.056. Epub 2011 May 13.

Abstract

Objective: To describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility.

Design: Case report from a randomized clinical trial.

Setting: Academic medical center.

Patient(s): A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor.

Intervention(s): Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity.

Main outcome measure(s): Pregnancy.

Result(s): A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle.

Conclusion(s): The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.

Trial registration: ClinicalTrials.gov NCT00730886.

Publication types

  • Case Reports
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Female
  • Humans
  • Infant, Newborn
  • Infertility, Female / diagnostic imaging
  • Infertility, Female / etiology
  • Infertility, Female / surgery*
  • Leiomyoma / complications
  • Leiomyoma / diagnostic imaging
  • Leiomyoma / surgery*
  • Magnetic Resonance Imaging* / methods
  • Pregnancy
  • Ultrasonography, Interventional* / methods
  • Uterine Neoplasms / complications
  • Uterine Neoplasms / diagnostic imaging
  • Uterine Neoplasms / surgery*

Associated data

  • ClinicalTrials.gov/NCT00730886