Raman-shifted alexandrite laser for soft tissue ablation in the 6- to 7-µm wavelength range

Biomed Opt Express. 2011 Apr 19;2(5):1275-81. doi: 10.1364/BOE.2.001275.

Abstract

Prior work with free-electron lasers (FELs) showed that wavelengths in the 6- to 7-µm range could ablate soft tissues efficiently with little collateral damage; however, FELs proved too costly and too complex for widespread surgical use. Several alternative 6- to 7-µm laser systems have demonstrated the ability to cut soft tissues cleanly, but at rates that were much too low for surgical applications. Here, we present initial results with a Raman-shifted, pulsed alexandrite laser that is tunable from 6 to 7 µm and cuts soft tissues cleanly-approximately 15 µm of thermal damage surrounding ablation craters in cornea-and does so with volumetric ablation rates of 2-5 × 10(-3) mm(3)/s. These rates are comparable to those attained in prior successful surgical trials using the FEL for optic nerve sheath fenestration.

Keywords: (140.2600) Free-electron lasers (FELs); (140.3070) Infrared and far-infrared lasers; (140.3550) Lasers, Raman; (170.1020) Ablation of tissue.