Genetic composition of six miniSTR in a Brazilian Mulatto sample population

Xavier G Aranda; Caroline A C Lage; John V Planz; Arthur J Eisenberg; Rodrigo S Moura-Neto; Rosane Silva

doi:10.1016/j.jflm.2011.02.003

Genetic composition of six miniSTR in a Brazilian Mulatto sample population

J Forensic Leg Med. 2011 May;18(4):184-6. doi: 10.1016/j.jflm.2011.02.003. Epub 2011 Mar 31.

Authors

Xavier G Aranda¹, Caroline A C Lage, John V Planz, Arthur J Eisenberg, Rodrigo S Moura-Neto, Rosane Silva

Affiliation

¹ UNT Center for Human Identification, University of North Texas Health Science Center, Forth Worth, TX 76107, USA. xaranda@hsc.unt.edu

PMID: 21550571
DOI: 10.1016/j.jflm.2011.02.003

Abstract

The present study characterizes the genetic variability of Mulatto population based on the polymorphism of six miniSTR autosomal loci, known as Non Codis 01 and 02 (NC01 and NC02) and evaluate their applicability in forensic genetics. A sample of 102 unrelated Brazilian mulattoes were genotyped for miniSTR loci D1S1677, D2S441, D4S2364 (miniplex NC02) and 45 individuals for D10S1248, D14S1434, D22S1045 (miniplex NC01). No significant deviations from Hardy-Weinberg equilibrium expectations were detected. The combined power of discrimination (PD) and mean power of exclusion (PE) were 0.999996 and 0.98991, respectively. The results also support the effectiveness of the NC01and NC02 miniplexes for human identification.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Brazil
DNA Fingerprinting
Ethnicity / genetics*
Gene Frequency
Genetic Variation*
Genetics, Population*
Genotype
Humans
Microsatellite Repeats*