Ultrasensitive protein detection using an aptamer-functionalized single polyaniline nanowire

Chem Commun (Camb). 2011 Jun 14;47(22):6368-70. doi: 10.1039/c1cc11353d. Epub 2011 May 6.

Abstract

A highly sensitive, conductometric and label-free biosensor for the detection of immunoglobulin E (IgE) is developed based on the immobilzation of the IgE aptamer onto a single polyaniline nanowire electrochemically synthesized in a facile and controllable way.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aniline Compounds / chemistry*
  • Aptamers, Nucleotide / chemistry*
  • Biomarkers / analysis
  • Biosensing Techniques / methods*
  • Immunoglobulin E / analysis*
  • Nanowires / chemistry*
  • Polymethyl Methacrylate / chemistry

Substances

  • Aniline Compounds
  • Aptamers, Nucleotide
  • Biomarkers
  • polyaniline
  • Immunoglobulin E
  • Polymethyl Methacrylate