High dosage of aripiprazole-induced dysphagia

Int J Eat Disord. 2012 Mar;45(2):305-6. doi: 10.1002/eat.20934. Epub 2011 May 3.

Abstract

Background: Dysphagia as a main manifestation of extrapyramidal symptoms is an uncommon adverse effect of second-generation antipsychotics.

Method: We present a 54-year-old drug-naïve patient with schizophrenia, who developed dysphagia with aripiprazole 30 mg daily treatment.

Results: This is the first case report on aripiprazole-induced dysphagia. We discuss the risk factors that led to dysphagia in this case.

Conclusion: Aripiprazole-induced dysphagia is rare, and it is important to be aware that it does occur with high-dosage treatment.

Publication types

  • Case Reports

MeSH terms

  • Antipsychotic Agents / administration & dosage
  • Antipsychotic Agents / adverse effects*
  • Antipsychotic Agents / therapeutic use
  • Aripiprazole
  • Deglutition Disorders / chemically induced*
  • Deglutition Disorders / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Piperazines / administration & dosage
  • Piperazines / adverse effects*
  • Piperazines / therapeutic use
  • Quinolones / administration & dosage
  • Quinolones / adverse effects*
  • Quinolones / therapeutic use
  • Schizophrenia / drug therapy*
  • Treatment Outcome

Substances

  • Antipsychotic Agents
  • Piperazines
  • Quinolones
  • Aripiprazole