Surface-functionalized fluorescent silica nanoparticles for the detection of ATP

Chem Commun (Camb). 2011 Jun 7;47(21):6066-8. doi: 10.1039/c1cc10419e. Epub 2011 Apr 26.

Abstract

The design of two-dyed fluorescent silica nanoparticles for ATP detection is presented. The indicator dye possesses a dipicolyl-amine (DPA) unit complexed with Zn(II) as a receptor function for ATP while a rhodamine derivative is used as the reference dye. The nanoparticles were fully characterized regarding analytical performance, morphology and cytocompatibility.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / analysis*
  • Amines / chemistry
  • Animals
  • Cell Line
  • Coordination Complexes / chemistry
  • Coordination Complexes / toxicity
  • Fluorescent Dyes / chemistry*
  • Microscopy, Fluorescence
  • Nanoparticles / chemistry*
  • Nanoparticles / toxicity
  • Picolinic Acids / chemistry
  • Rats
  • Silicon Dioxide / chemistry*
  • Spectrometry, Fluorescence / methods*
  • Surface Properties
  • Zinc / chemistry

Substances

  • 2,2'-dipicolylamine
  • Amines
  • Coordination Complexes
  • Fluorescent Dyes
  • Picolinic Acids
  • Silicon Dioxide
  • Adenosine Triphosphate
  • Zinc