Doppler assessment between pathological examination of the placenta and late fetal intrauterine demise

Clin Exp Obstet Gynecol. 2011;38(1):43-5.

Abstract

Aim: The relation between placental histopathological examination, umbilical cord pathology and abnormal umbilical and cerebral Doppler as a predictor of stillbirth at later gestations was evaluated.

Materials and methods: A retrospective study of 55 monofetal pregnancies complicated with late fetal death from 2005-2008 was conducted at the Institute of Gynecology and Obstetrics, Bel-grade.

Statistical analysis: chi-square likelihood ratio test and Spearman's coefficient correlation.

Results: Intrauterine fetal demise occurred most frequently at term -32.7% of the time. Changes in the umbilical artery resistance index were not significantly different from placental histopathology findings, p = 0.363. There was a significant correlation between neonatal birth weight and weeks of gestation at delivery, r = 0.796; p = 0.001.

Conclusion: Umbilical artery Doppler is a relatively poor predictor of stillbirths due to placental dysfunction. It seems that neonatal birth weight is the best predictor of late stillbirth in high-risk pregnancies.

MeSH terms

  • Adult
  • Birth Weight / physiology
  • Blood Flow Velocity / physiology
  • Female
  • Fetal Death / diagnostic imaging*
  • Fetal Death / pathology*
  • Humans
  • Placenta / diagnostic imaging*
  • Placenta / pathology*
  • Pregnancy
  • Retrospective Studies
  • Ultrasonography, Doppler / methods
  • Umbilical Arteries / diagnostic imaging
  • Umbilical Arteries / pathology