Use of letrozole challenge test to adjust gonadotropin dose in non-down-regulated cycles

Yaakov Bentov; Eliezer Burstein; Navid Esfandiari; Robert F Casper

doi:10.1016/j.fertnstert.2011.03.042

Use of letrozole challenge test to adjust gonadotropin dose in non-down-regulated cycles

Fertil Steril. 2011 Jun 30;95(8):2492-3. doi: 10.1016/j.fertnstert.2011.03.042. Epub 2011 Apr 9.

Authors

Yaakov Bentov¹, Eliezer Burstein, Navid Esfandiari, Robert F Casper

Affiliation

¹ Toronto Centre for Advanced Reproductive Technology, Toronto, Ontario, Canada. bentov@lunenfeld.ca

PMID: 21481375
DOI: 10.1016/j.fertnstert.2011.03.042

Abstract

The use of a letrozole challenge test to predict ovarian response is described. The authors show that a ratio of cycle day 7 to cycle day 3 post-letrozole FSH level >1.5 is associated with poor ovarian response.

MeSH terms

Aromatase Inhibitors*
Biomarkers / blood
Drug Administration Schedule
Estradiol / blood
Female
Fertility Agents, Female / administration & dosage*
Follicle Stimulating Hormone, Human / blood
Gonadotropins / administration & dosage*
Humans
Letrozole
Luteinizing Hormone / blood
Nitriles*
Ontario
Ovarian Function Tests*
Ovulation / drug effects*
Ovulation Induction / methods*
Predictive Value of Tests
Pregnancy
Retrospective Studies
Time Factors
Treatment Outcome
Triazoles*

Substances

Aromatase Inhibitors
Biomarkers
Fertility Agents, Female
Follicle Stimulating Hormone, Human
Gonadotropins
Nitriles
Triazoles
Estradiol
Letrozole
Luteinizing Hormone