The adoption of invasive coronary physiologic lesion assessment before percutaneous coronary intervention has become routine in many catheterization laboratories. In the last decade, numerous studies have demonstrated favorable outcomes for revascularization decisions based on in-lab coronary physiology in many patients. The use of coronary physiology in the laboratory has been identified as a class IIa recommendation for patients in whom the clinical presentation and supporting data are too inconclusive to make an objective decision regarding treatment. This article reviews pertinent concepts and studies of the more complex applications of translesional pressure measurements for optimal patient outcomes.
Published by Elsevier Inc.