Gene copy number variations: it is important to determine which allele is affected

Pharmacogenomics. 2011 Mar;12(3):299-301. doi: 10.2217/pgs.11.5.
No abstract available

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural

MeSH terms

  • Alleles
  • Cytochrome P-450 CYP2D6 / genetics*
  • DNA Copy Number Variations*
  • Dextromethorphan / pharmacokinetics
  • Dextromethorphan / therapeutic use
  • Gene Amplification
  • Gene Deletion
  • Gene Dosage*
  • Genetic Association Studies
  • Humans
  • Inactivation, Metabolic / genetics
  • Phenotype

Substances

  • Dextromethorphan
  • Cytochrome P-450 CYP2D6