An organometallic derivative of a BAPTA ligand: towards electrochemically controlled cation release in biocompatible media

Chem Commun (Camb). 2011 May 14;47(18):5199-201. doi: 10.1039/c1cc11081k. Epub 2011 Mar 29.

Abstract

The combination of a ferrocenyl moiety with BAPTA provides a novel, water-soluble, redox-active chelator. This chelator behaving as a conformational sensor exhibits an unexpected electrochemical response with high affinity and selectivity for calcium.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Calcium / chemistry*
  • Calcium / metabolism*
  • Cations / chemistry*
  • Chelating Agents / chemistry*
  • Egtazic Acid / analogs & derivatives*
  • Egtazic Acid / chemistry
  • Electrochemistry
  • Ferrous Compounds / chemistry*
  • Ligands
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Solubility
  • Water / chemistry

Substances

  • Cations
  • Chelating Agents
  • Ferrous Compounds
  • Ligands
  • Organometallic Compounds
  • Water
  • Egtazic Acid
  • 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid
  • Calcium