Granulocytic sarcoma of the knee and the spine as aleukemic relapse of acute myeloid leukemia in a child

J Pediatr Hematol Oncol. 2011 Aug;33(6):480-1. doi: 10.1097/MPH.0b013e3181faf8b0.

Abstract

Granulocytic sarcoma is a very rare disease in childhood, which may precede the clinical manifestations of acute myeloid leukemia or may occur as a relapse of a nonleukemic acute myeloid leukemia. It is a malignant, solid tumor consisting of myeloblasts or immature myeloid cells occurring in extramedullary sites. We report interesting magnetic resonance images of a nonleukemic relapse of acute myeloid leukemia in a child presenting as a granulocytic sarcoma unusually localized to the knee and spine.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Chromosomes, Human, Pair 11 / genetics
  • Combined Modality Therapy
  • Female
  • Gene Rearrangement
  • Humans
  • Knee / pathology*
  • Leukemia, Monocytic, Acute / complications
  • Leukemia, Monocytic, Acute / pathology*
  • Leukemia, Monocytic, Acute / therapy
  • Magnetic Resonance Imaging
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / etiology
  • Neoplasm Recurrence, Local / therapy*
  • Remission Induction
  • Sarcoma, Myeloid / etiology
  • Sarcoma, Myeloid / therapy*
  • Spinal Neoplasms / etiology
  • Spinal Neoplasms / therapy*
  • Treatment Outcome