Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage

J Clin Microbiol. 2011 May;49(5):1972-4. doi: 10.1128/JCM.01742-10. Epub 2011 Mar 23.

Abstract

Among bullous impetigo isolates, exfoliative toxin (ET) gene carriage was found in 61.5% of methicillin-resistant Staphylococcus aureus (MRSA) isolates versus 90.6% of methicillin-susceptible S. aureus (MSSA) isolates. MRSA-only cases were ETB or ETA positive, while MRSA/MSSA coinfection cases were ET negative for MRSA but ETA positive for MSSA. Collagen adhesin may facilitate some MRSA infections.

MeSH terms

  • Adhesins, Bacterial / biosynthesis
  • Adhesins, Bacterial / genetics
  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Exfoliatins / biosynthesis*
  • Exfoliatins / genetics
  • Humans
  • Impetigo / microbiology*
  • Infant
  • Methicillin Resistance
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / genetics
  • Staphylococcus aureus / isolation & purification*
  • Virulence Factors / biosynthesis*
  • Virulence Factors / genetics

Substances

  • Adhesins, Bacterial
  • Exfoliatins
  • Virulence Factors
  • adhesin, Staphylococcus aureus