[The role of adjuvant chemotherapy in operable non-small cell lung cancer]

Zhongguo Fei Ai Za Zhi. 2011 Mar;14(3):281-5. doi: 10.3779/j.issn.1009-3419.2011.03.15.
[Article in Chinese]

Abstract

Postoperative recurrence is the main cause of primary treatment failure in the resectable non-small cell lung cancer (NSCLC). Systematic treatments should be taken to decrease the recurrence. Adjuvant chemotherapy, including neoadjuvant chemotherapy, postoperative adjuvant chemotherapy and targeted therapy, is a widely used in this area. In this review, we summarize the clinical trials and meta-analysis related to the adjuvant chemotherapy and targeted therapy in patients with early stage NSCLC.

肺癌患者术后复发转移是临床治疗失败的主要原因,因此亟待一种更系统的治疗手段来完善患者的治疗计划,以降低复发率、延长生存期。辅助化疗(包括新辅助化疗、术后辅助化疗、靶向药物辅助化疗)应运而生。本文就辅助治疗领域的研究进展进行综述。

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Carcinoma, Non-Small-Cell Lung / surgery*
  • Chemotherapy, Adjuvant
  • Clinical Trials as Topic
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / surgery*
  • Postoperative Period
  • Preoperative Period