Invasive Candida infections in solid organ transplant recipient children

Expert Rev Anti Infect Ther. 2011 Mar;9(3):317-24. doi: 10.1586/eri.11.6.

Abstract

Solid organ transplantation (SOT) is now an accepted therapy for many end-stage organ disorders and fungal infections are the principal cause of infection-related mortality in SOT recipients. Among invasive fungal infections, Candida species are the most common pathogens identified, associated with high mortality rates. The epidemiology and clinical manifestations of Candida infections vary with the type of organ transplantation. This article reviews invasive Candida infections in pediatric SOT recipients.

Publication types

  • Review

MeSH terms

  • Antifungal Agents / administration & dosage
  • Antifungal Agents / therapeutic use*
  • Candidiasis, Invasive / complications*
  • Candidiasis, Invasive / diagnosis
  • Candidiasis, Invasive / epidemiology
  • Candidiasis, Invasive / therapy
  • Chemoprevention
  • Child
  • Humans
  • Organ Transplantation*
  • Postoperative Complications / diagnosis
  • Postoperative Complications / epidemiology
  • Postoperative Complications / microbiology*
  • Postoperative Complications / therapy
  • Risk Factors

Substances

  • Antifungal Agents