Synthesis of (-)-viriditoxin: a 6,6'-binaphthopyran-2-one that targets the bacterial cell division protein FtsZ

Angew Chem Int Ed Engl. 2011 Apr 11;50(16):3730-3. doi: 10.1002/anie.201007298. Epub 2011 Mar 16.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aspergillus / chemistry
  • Bacteria / metabolism
  • Bacterial Proteins / antagonists & inhibitors*
  • Bacterial Proteins / metabolism
  • Catalysis
  • Crystallography, X-Ray
  • Cytoskeletal Proteins / antagonists & inhibitors*
  • Cytoskeletal Proteins / metabolism
  • Molecular Conformation
  • Naphthols / chemical synthesis
  • Naphthols / chemistry
  • Stereoisomerism
  • Vanadium / chemistry

Substances

  • Bacterial Proteins
  • Cytoskeletal Proteins
  • FtsZ protein, Bacteria
  • Naphthols
  • Vanadium
  • viriditoxin