An evolutionarily conserved pseudokinase mediates stem cell production in plants

Plant Cell. 2011 Mar;23(3):851-4. doi: 10.1105/tpc.110.075622. Epub 2011 Mar 11.

Abstract

Sequence comparisons, biochemical experiments, and studies with mutants in transgenic plants show that the Arabidopsis protein CORYNE, currently thought to be a kinase that acts as part of a receptor kinase complex, is likely to be a pseudokinase and not a kinase.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Arabidopsis / enzymology*
  • Arabidopsis / genetics
  • Arabidopsis Proteins / metabolism*
  • Cell Membrane / metabolism*
  • Cloning, Molecular
  • Evolution, Molecular
  • Gene Expression Regulation, Plant
  • Genetic Complementation Test
  • Membrane Proteins / metabolism
  • Mutation
  • Plants, Genetically Modified / enzymology
  • Plants, Genetically Modified / genetics
  • Protein Serine-Threonine Kinases
  • Receptor Protein-Tyrosine Kinases / chemistry*
  • Receptor Protein-Tyrosine Kinases / genetics
  • Receptor Protein-Tyrosine Kinases / metabolism
  • Receptors, Cell Surface
  • Recombinant Fusion Proteins
  • Signal Transduction
  • Stem Cells / physiology
  • Transgenes

Substances

  • AT2G27250 protein, Arabidopsis
  • Arabidopsis Proteins
  • CLV2 protein, Arabidopsis
  • Membrane Proteins
  • Receptors, Cell Surface
  • Recombinant Fusion Proteins
  • Receptor Protein-Tyrosine Kinases
  • CLV1 protein, Arabidopsis
  • CORYNE protein, Arabidopsis
  • Protein Serine-Threonine Kinases