Concomitant unilateral and synchronous bilateral testis cancer in azoospermic dizygotic twins: differential management of fertility preservation

Abstract

Objective: To optimize fertility preservation management in unilateral or bilateral testicular cancer.

Design: Case series.

Setting: Urology department and reproductive biology laboratory.

Patient(s): Dizygotic azoospermic twins presenting unilateral and bilateral synchronous testicular tumors.

Intervention(s): Testicular sperm extraction (TESE) and orchiectomy.

Main outcome measure(s): Semen analysis, histologic diagnosis.

Result(s): No spermatozoa were cryopreserved for the first case, because fertility preservation was proposed after orchiectomy. Spermatozoa were retrieved after TESE for his brother with bilateral tumor.

Conclusion(s): Clinicians should be aware of the need to recommend sperm banking before treatments may alter spermatogenesis. TESE may be the sole option for fertility preservation in bilateral testicular cancer.