Living cell imaging by far-field fibered interference scanning optical microscopy

Opt Express. 2011 Jan 31;19(3):2702-10. doi: 10.1364/OE.19.002702.

Abstract

We report on the imaging of biological cells including living neurons by a dedicated fibered interferometric scanning optical microscope. The topography and surface roughness of mouse fibroblasts and hippocampal neurons are clearly revealed. This straightforward far-field technique allows fast, high resolution observation of samples in liquids without lengthy alignment procedures or costly components.

MeSH terms

  • Animals
  • Cells, Cultured
  • Equipment Design
  • Equipment Failure Analysis
  • Fiber Optic Technology / instrumentation*
  • Fibroblasts / cytology*
  • Image Enhancement / instrumentation*
  • Mice
  • Microscopy, Confocal / instrumentation*
  • Microscopy, Interference / instrumentation*
  • Neurons / cytology*