[A case of coexisting malignant mesothelioma and squamous cell carcinoma of the lung]

Gan To Kagaku Ryoho. 2011 Feb;38(2):267-70.
[Article in Japanese]

Abstract

We experienced a case of malignant mesothelioma with squamous cell carcinoma of the lung concurrently. A 40-year-old man presented with dyspnea. A massive pleural effusion was found by X-ray in the right side of his chest. Transcutaneous pleural biopsy yielded a diagnosis of malignant mesothelioma(IMIG cT4N0M0, Stage IV ). At the same time, his chest CT revealed tumor in the right hilar lesion. Transbronchial lung biopsy yielded a diagnosis of squamous cell carcinoma of the lung (cT3N0M0, Stage III B). Our diagnosis was double cancer, malignant mesothelioma and lung cancer. Chemotherapy with carboplatin, gemcitabine and radiation therapy was performed, but the patient died from deterioration of his systemic condition. We encountered a rare case of double cancer. More attention must be paid in making a diagnosis of malignant mesothelioma and lung cancer.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy
  • Carboplatin / administration & dosage
  • Carboplatin / therapeutic use
  • Carcinoma, Squamous Cell / blood supply
  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / pathology*
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives
  • Deoxycytidine / therapeutic use
  • Disease Progression
  • Fatal Outcome
  • Gemcitabine
  • Humans
  • Lung Neoplasms / blood supply
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / pathology*
  • Male
  • Mesothelioma / blood supply
  • Mesothelioma / diagnostic imaging
  • Mesothelioma / drug therapy
  • Mesothelioma / pathology*
  • Neoplasms, Multiple Primary / blood supply
  • Neoplasms, Multiple Primary / diagnostic imaging
  • Neoplasms, Multiple Primary / drug therapy
  • Neoplasms, Multiple Primary / pathology*
  • Neovascularization, Pathologic / drug therapy
  • Tomography, X-Ray Computed

Substances

  • Deoxycytidine
  • Carboplatin
  • Gemcitabine