Objective: To investigate the compatible stability of Reduning injection in different dosages with 5% glucose injection and 0.9% sodium chloride injection.
Method: The changes before and after compatible application of Reduning injection with 5% glucose injection and 0.9% sodium chloride injection (5: 250, 10: 250, 20: 250, 30: 250, 40: 250, 50: 250, 62. 5: 250) on color, clarity, pH, main ingredients and atlas of HPLC were determined.
Result: There were no difference in the color, clarity, pH, the main ingredients and liquid fingerprints of the mixture solutions, but the insoluble particles in them showed significant difference within 6 h.
Conclusion: Reduning injection is compatible in different concentrations with 5% glucose injection or 0.9% sodium chloride injection within 4 h, in clinic, it should be used within 2 h, the volume of Reduning injection with 5% glucose injection or 0.9% sodium chloride injection should be no more than 50 mL.