Applicability of the 9Be(d,n)10B reaction to AB-BNCT skin and deep tumor treatment

M E Capoulat; D M Minsky; A J Kreiner

doi:10.1016/j.apradiso.2011.02.015

Applicability of the 9Be(d,n)10B reaction to AB-BNCT skin and deep tumor treatment

Appl Radiat Isot. 2011 Dec;69(12):1684-7. doi: 10.1016/j.apradiso.2011.02.015. Epub 2011 Feb 15.

Authors

M E Capoulat¹, D M Minsky, A J Kreiner

Affiliation

¹ Gerencia de Investigación y Aplicaciones, CNEA, San Martín, Buenos Aires, Argentina. capoulat@tandar.cnea.gov.ar

PMID: 21353576
DOI: 10.1016/j.apradiso.2011.02.015

Abstract

In the range of low bombarding energies (less than about 1.5 MeV) the (9)Be(d,n)(10)B reaction produces neutron spectra that can be moderated depending on the choice of the target thickness and the deuteron bombarding energy. In this work, a Monte Carlo simulation study to determine the capability of this reaction to deliver enough dose to efficiently control both skin and deep seated tumors has been performed by means of MCNP calculations using eight optimized (9)Be targets.

MeSH terms

Beryllium / therapeutic use*
Boron Neutron Capture Therapy*
Humans
Monte Carlo Method
Neoplasms / radiotherapy*
Radioisotopes / therapeutic use*
Skin Neoplasms / radiotherapy*

Substances

Radioisotopes
Beryllium