Expression of mast cell-associated genes is upregulated in adult eosinophilic esophagitis and responds to steroid or dietary therapy

J Allergy Clin Immunol. 2011 May;127(5):1307-8.e3. doi: 10.1016/j.jaci.2010.12.1118. Epub 2011 Feb 18.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Androstadienes / pharmacology
  • Androstadienes / therapeutic use*
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use*
  • Carboxypeptidases A / genetics
  • Carboxypeptidases A / metabolism
  • Chemokine CCL26
  • Chemokines, CC / genetics
  • Chemokines, CC / metabolism
  • Eosinophilic Esophagitis / diet therapy
  • Eosinophilic Esophagitis / drug therapy
  • Eosinophilic Esophagitis / immunology
  • Eosinophilic Esophagitis / physiopathology*
  • Female
  • Fluticasone
  • Gene Expression / drug effects*
  • Humans
  • Male
  • Mast Cells / immunology
  • Mast Cells / metabolism*
  • Middle Aged
  • Steroids / pharmacology
  • Steroids / therapeutic use
  • Treatment Outcome
  • Up-Regulation*

Substances

  • Androstadienes
  • Anti-Inflammatory Agents
  • CCL26 protein, human
  • Chemokine CCL26
  • Chemokines, CC
  • Steroids
  • Fluticasone
  • CPA3 protein, human
  • Carboxypeptidases A