Abstract
The two structurally interesting bioorganometallic analogues of muramyldipeptide (MDP) with potential immunomodulatory activity were synthesized starting from the O-protected N-acetylmuramic acid (MurNAc), L- or D-Ala and 1'-aminoferrocene-1-carboxylic acid (Fca). They were fully characterized by IR, (1)H NMR, (13)C NMR and CD spectroscopy as well as by FD mass spectrometry.
Copyright © 2011 Elsevier Ltd. All rights reserved.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Carboxylic Acids / chemistry*
-
Circular Dichroism
-
Ferrous Compounds / chemistry*
-
Hydrogen Bonding
-
Magnetic Resonance Spectroscopy
-
Mass Spectrometry
-
Metallocenes
-
Molecular Structure
-
Muramic Acids / chemistry*
-
Peptides / chemical synthesis*
-
Peptides / chemistry*
Substances
-
1'-aminoferrocene-1-carboxylic acid
-
Carboxylic Acids
-
Ferrous Compounds
-
Metallocenes
-
Muramic Acids
-
Peptides
-
N-acetylmuramic acid
-
ferrocene